RCEES OpenIR  > 土壤环境科学实验室
Nutritional status affects the bioaccessibility and speciation of arsenic from soils in a simulator of the human intestinal microbial ecosystem
Wang, Pengfei; Yin, Naiyi; Cai, Xiaolin; Du, Huili; Li, Zejiao; Sun, Guoxin; Cui, Yanshan
2018-12-10
Source PublicationSCIENCE OF THE TOTAL ENVIRONMENT
ISSN0048-9697
Volume644Pages:815-821
AbstractArsenic (As) is a highly toxic contaminant in food and soil. In this study, we investigated the effects of four nutritional states (including a fed state with vitamin C, a fed state with protein powder, a fed state with glucose and a fasted state) on the variability of soil As bioaccessibility and biotransformation using the physiologically based extraction test (PBET) combined with a simulator of the human intestinal microbial ecosystem model (SHIME). The results indicated that the vitamin C and protein powder increased As bioaccessibility in gastric digests. In the colon phase, As bioaccessibility was observably enhanced by protein powder, and it varied under the vitamin C and glucose conditions. Additionally, the order of As methylation percentages in the four nutritional states was protein powder > vitamin C > fasted state > glucose (except S2); As bioaccessibility increased 1.3-13.7% and 15.8-35.4% in treatments of the vitamin C and protein powder, respectively. Meanwhile, large amounts of monomethylarsonic acid (MMA(V)) were observed in the colon digest in the protein powder condition. In contrast, As methylation was significantly decreased with the addition of glucose, with a decline of 25.9-45.5%. Additionally, glucose enhanced the reduction of As(V). Therefore, nutritional status is a crucial parameter for the prediction of bioaccessibility and speciation of As when assessing health risks from As following oral exposure. (C) 2018 Elsevier B.V. All rights reserved.
Department土壤环境科学实验室
KeywordArsenic Nutritional status Bioaccessibility Speciation SHIME Soil
Document Type期刊论文
Identifierhttp://ir.rcees.ac.cn/handle/311016/41224
Collection土壤环境科学实验室
Recommended Citation
GB/T 7714
Wang, Pengfei,Yin, Naiyi,Cai, Xiaolin,et al. Nutritional status affects the bioaccessibility and speciation of arsenic from soils in a simulator of the human intestinal microbial ecosystem[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2018,644:815-821.
APA Wang, Pengfei.,Yin, Naiyi.,Cai, Xiaolin.,Du, Huili.,Li, Zejiao.,...&Cui, Yanshan.(2018).Nutritional status affects the bioaccessibility and speciation of arsenic from soils in a simulator of the human intestinal microbial ecosystem.SCIENCE OF THE TOTAL ENVIRONMENT,644,815-821.
MLA Wang, Pengfei,et al."Nutritional status affects the bioaccessibility and speciation of arsenic from soils in a simulator of the human intestinal microbial ecosystem".SCIENCE OF THE TOTAL ENVIRONMENT 644(2018):815-821.
Files in This Item: Download All
File Name/Size DocType Version Access License
Nutritional status a(1189KB)期刊论文出版稿开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wang, Pengfei]'s Articles
[Yin, Naiyi]'s Articles
[Cai, Xiaolin]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wang, Pengfei]'s Articles
[Yin, Naiyi]'s Articles
[Cai, Xiaolin]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wang, Pengfei]'s Articles
[Yin, Naiyi]'s Articles
[Cai, Xiaolin]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Nutritional status affects the bioaccessibility and speciation of arsenic from soils in a simulator of the human intestinal microbial ecosystem.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.