| Evaluation of combined toxicity of Siduron and cadmium on earthworm (Eisenia fetida) using Biomarker Response Index | |
Li, Xuzhi; Wang, Meie; Chen, Weiping ; Jiang, Rong
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| 2019-01-01 | |
| Source Publication | SCIENCE OF THE TOTAL ENVIRONMENT
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| ISSN | 0048-9697 |
| Volume | 646Pages:893-901 |
| Abstract | Agrochemicals and heavy metals are widespread contaminants in urban soil and could co-exist as mixture, which could cause unexpected risk to terrestrial organism. To assess the joint effect of herbicide Siduron and Cd, a battery of sub-lethal biomarkers was studied using earthworm ecotoxicological assay. Most selected biomarkers appeared significant but complicated responses with the increasing concentration of contaminants after 28-day exposure. In order to quantify the overall effect of the mixture contaminants, Biomarker Response Index (BRI) was used to integrate the multiple responses. Concentration Addition Index (CAI) and Effect Addition Index (EAI) were introduced to assess types of joint effect. Results showed significantly dose-effect responses between BRI and contaminant exposure concentrations. Integrated toxicity increased obviously under joint treatments of Siduron and Cd compared to their individual treatments. According to CAI, a clear antagonism was observed at relatively lower effects and gradually transformed to slight synergism with an increase of effects, while EAI showed the joint effect of addition at the whole range of effect levels. Thus, compared to the simple analysis of those complicated responses, BRI is an effective method to determine the integrated toxicity of mixture and its combination with joint effect indices (CAI and EAI) provides more worthy risk assessment on toxicity interaction among compounds. (C) 2018 Published by Elsevier B.V. |
| Department | 城市与区域生态国家重点实验室 |
| Keyword | Joint stress Multi-biomarker responses Biomarker Response Index Concentration Addition Index Effect Addition Index |
| Document Type | 期刊论文 |
| Identifier | http://ir.rcees.ac.cn/handle/311016/42847 |
| Collection | 城市与区域生态国家重点实验室 |
| Affiliation | 1.Minist Ecol & Environm, Nanjing Inst Environm Sci, State Environm Protect Key Lab Soil Environm Mana, Nanjing 210042, Jiangsu, Peoples R China 2.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Urban & Reg Ecol, Beijing 100085, Peoples R China |
| Recommended Citation GB/T 7714 | Li, Xuzhi,Wang, Meie,Chen, Weiping,et al. Evaluation of combined toxicity of Siduron and cadmium on earthworm (Eisenia fetida) using Biomarker Response Index[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2019,646:893-901. |
| APA | Li, Xuzhi,Wang, Meie,Chen, Weiping,&Jiang, Rong.(2019).Evaluation of combined toxicity of Siduron and cadmium on earthworm (Eisenia fetida) using Biomarker Response Index.SCIENCE OF THE TOTAL ENVIRONMENT,646,893-901. |
| MLA | Li, Xuzhi,et al."Evaluation of combined toxicity of Siduron and cadmium on earthworm (Eisenia fetida) using Biomarker Response Index".SCIENCE OF THE TOTAL ENVIRONMENT 646(2019):893-901. |
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| Evaluation of combin（1630KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Download | |
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