| Total Synthesis of (-)-Orthodiffenes A and C | |
| Liu, Jun; Liu, Yi; Zhang, Xing; Zhang, Chaoli; Gao, Yangguang; Wang, LinLin; Du, Yuguo | |
| 2012 | |
| Source Publication | JOURNAL OF ORGANIC CHEMISTRY
 |
| ISSN | 0022-3263 |
| Volume | 77Issue:21Pages:9718－9723 |
| Abstract | The efficient and concise synthesis of (-)-orthodiffenes A and C has been accomplished for the first time in eight steps from readily available chiral synthons, D-mannose and D-ethyl lactate. Our work confirmed the complete structure of orthodiffenes A and C, including their absolute stereochemistry. The key steps of our total synthesis involved cis-fused tetrahydrofuran cyclization, one-pot deprotection-lactonization, and intramolecular benzoyl migration according to a biosynthetic hypothesis of orthodiffenes. |
| Department | 环境化学与生态毒理学国家重点实验室 |
| WOS ID | WOS:000311190200031 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.rcees.ac.cn/handle/311016/7723 |
| Collection | 环境化学与生态毒理学国家重点实验室 |
| Recommended Citation GB/T 7714 | Liu, Jun,Liu, Yi,Zhang, Xing,et al. Total Synthesis of (-)-Orthodiffenes A and C[J]. JOURNAL OF ORGANIC CHEMISTRY,2012,77(21):9718－9723. |
| APA | Liu, Jun.,Liu, Yi.,Zhang, Xing.,Zhang, Chaoli.,Gao, Yangguang.,...&Du, Yuguo.(2012).Total Synthesis of (-)-Orthodiffenes A and C.JOURNAL OF ORGANIC CHEMISTRY,77(21),9718－9723. |
| MLA | Liu, Jun,et al."Total Synthesis of (-)-Orthodiffenes A and C".JOURNAL OF ORGANIC CHEMISTRY 77.21(2012):9718－9723. |
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