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Cancer risk assessment on trihalomethanes and haloacetic acids in drinking water of China using disability-adjusted life years
Pan, Shenling; An, Wei; Li, Hongyan; Su, Ming; Zhang, Jinliang; Yang, Min
2014
Source PublicationJOURNAL OF HAZARDOUS MATERIALS
ISSN0304-3894
Volume280Issue:1Pages:288-294
AbstractThe cancer risks from exposure to trihalomethanes (THMs) and haloacetic acids (HAM) through multiple pathways were assessed based on the result of a water quality survey in 35 major cities of China. To express the risks in disability-adjusted life years (DALYs), the excess cancer incidence estimates were combined with a two-stage disease model for calculation. The median total cancer risk of THMs and HAAs was calculated as 7.34 x 10(-7) DALYs per person-year (ppy), lower than the reference level of risk (10(-6) DALYs ppy) set by WHO. The risk from ingestion and inhalation exposures contributed 93.6% and 6.3% of the total risk respectively, while dermal contact made a negligible contribution. The median risk of trichloroacetic acid (TCAA) (2.12 x 10(-7) DALYs ppy) was highest among the disinfection by-products (DBPs) considered. The risk ratio of total HAAs (THAA) to total THMs (TTHM) was 1.12. The risk was highest in northeast China while lowest in northwest China. As for the 35 cities, Tianjin had the highest risk while Yinchuan had the lowest. This study attempted to use DALYs for the risk assessment of DBPs, which will provide useful information for risk comparison and prioritization of hazards in drinking water. (C) 2014 Elsevier B.V. All rights reserved.
Department环境水质学国家重点实验室
KeywordDisinfection By-products Trihalomethanes Haloacetic Acids Cancer Risk Assessment Disability-adjusted Life Years
WOS IDWOS:000344428700034
Citation statistics
Cited Times:39[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.rcees.ac.cn/handle/311016/9506
Collection环境水质学国家重点实验室
Recommended Citation
GB/T 7714
Pan, Shenling,An, Wei,Li, Hongyan,et al. Cancer risk assessment on trihalomethanes and haloacetic acids in drinking water of China using disability-adjusted life years[J]. JOURNAL OF HAZARDOUS MATERIALS,2014,280(1):288-294.
APA Pan, Shenling,An, Wei,Li, Hongyan,Su, Ming,Zhang, Jinliang,&Yang, Min.(2014).Cancer risk assessment on trihalomethanes and haloacetic acids in drinking water of China using disability-adjusted life years.JOURNAL OF HAZARDOUS MATERIALS,280(1),288-294.
MLA Pan, Shenling,et al."Cancer risk assessment on trihalomethanes and haloacetic acids in drinking water of China using disability-adjusted life years".JOURNAL OF HAZARDOUS MATERIALS 280.1(2014):288-294.
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