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大气细颗粒物对血浆关键蛋白酶系相互作用 和血小板生成的影响及机理研究 学位论文
理学, 北京: 中国科学院生态环境研究中心, 2019
Authors:  晋小婷
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大气细颗粒物  血液效应  血浆蛋白酶系  巨核细胞  血小板  airborne Fine Particles, Hematological Effect, Plasma Protease System, Megakaryocyte, Platelet  
Per- and polyfluoroalkyl substances display structure-dependent inhibition towards UDP-glucuronosyltransferases 期刊论文
ENVIRONMENTAL POLLUTION, 2019, 卷号: 254, 页码: -
Authors:  Liu, Yong-Zhe;  Zhang, Zhi-Peng;  Fu, Zhi-Wei;  Yang, Kun;  Ding, Ning;  Hu, Li-Gang;  Fang, Zhong-Ze;  Zhuo, Xiaozhen
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Per- and polyfluoroalkyl substances (PFASs)  UDP-Glucuronosyltransferases (UGTs)  Half inhibition concentration (IC50)  Inhibition type  Inhibition kinetic parameters (Ki)  In vitro-in vivo extrapolation (IVIVE)  
Airborne Fine Particles Induce Hematological Effects through Regulating the Crosstalk of the Kallikrein-Kinin, Complement, and Coagulation Systems 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2019, 卷号: 53, 期号: 5, 页码: 2840-2851
Authors:  Jin, Xiaoting;  Ma, Qianchi;  Sun, Zhendong;  Yang, Xuezhi;  Zhou, Qunfang;  Qu, Guangbo;  Liu, Qian;  Liao, Chunyang;  Li, Zhuoyu;  Jiang, Guibin
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Exploring the Heterogeneity of Nanoparticles in Their Interactions with Plasma Coagulation Factor XII 期刊论文
ACS NANO, 2019, 卷号: 13, 期号: 2, 页码: 1990-2003
Authors:  Hao, Fang;  Liu, Qian S.;  Chen, Xi;  Zhao, Xingchen;  Zhou, Qunfang;  Liao, Chunyang;  Jiang, Guibin
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nanoparticles  coagulation factor XII  heterogeneity  conformational change  enzymatic activity  
Anti-estrogenic activity of tris(2,3-dibromopropyl) isocyanurate through disruption of co-activator recruitment: experimental and computational studies 期刊论文
ARCHIVES OF TOXICOLOGY, 2018, 卷号: 92, 期号: 4, 页码: 1471-1482
Authors:  Cao, Huiming;  Li, Xun;  Zhang, Wenjuan;  Wang, Ling;  Pan, Yu;  Zhou, Zhen;  Chen, Minjie;  Zhang, Aiqian;  Liang, Yong;  Song, Maoyong
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Tris(2,3-dibromopropyl) isocyanurate  MVLN assays  AF-2 site  Molecular dynamics simulations  
Perfluorohexadecanoic acid increases paracellular permeability in endothelial cells through the activation of plasma kallikrein-kinin system 期刊论文
CHEMOSPHERE, 2018, 卷号: 190, 页码: 191-200
Authors:  Liu, Qian S.;  Hao, Fang;  Sun, Zhendong;  Long, Yanmin;  Zhou, Qunfang;  Jiang, Guibin
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Per- and polyfluoroalkyl substances  Kallikrein-kinin system  Endothelial cells  Paracellular permeability  Adherens junctions  Vascular endothelial cadherin  
Structure-Dependent Hematological Effects of Per- and. Polyfluoroalkyl Substances on Activation of Plasma Kallikrein-Kinin System Cascade 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2017, 卷号: 51, 期号: 17, 页码: 10173-10183
Authors:  Liu, Qian S.;  Sun, Yuzhen;  Qu, Guangbo;  Long, Yanmin;  Zhao, Xingchen;  Zhang, Aiqian;  Zhou, Qunfang;  Hu, Ligang;  Jiang, Guibin
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新型有机卤代化合物的神经毒理学效应与作用机制研究 学位论文
, 北京: 中国科学院大学, 2017
Authors:  刘倩
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新型有机卤代化合物  四溴双酚 A衍生物  Emerging Halogenated Organic Compounds  全氟及多氟烷基化合物  Tetrabromobisphenol Aderivatives  神经毒性  Per-and Polyfluoroalkyl Substances  血管舒缓素-激肽系统  Neurotoxicity  Plasma Kallikrein-kinin System  
纳米银表面修饰对其生物学效应的调控作用及分子机制研究 学位论文
, 北京: 中国科学院研究生院, 2015
Authors:  龙艳敏
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纳米银  表面修饰  氧化应激  接触体系  生物转化  Nanosilver  Surface Modification  Oxidative Stress  Kallikrein-kinin System  Biotransformation