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Typical halogenated flame retardants affect human neural stem cell gene expression during proliferation and differentiation via glycogen synthase kinase 3 beta and T3 signaling 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 183, 页码: -
Authors:  Liang, Shaojun;  Liang, Shengxian;  Zhou, Hui;  Yin, Nuoya;  Faiola, Francesco
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Human neural stem cells (hNSCs)  TBBPA/TBBPS/TCBPA  BDE-209/BDE-47  Human neural developmental toxicity  GSK3 beta  T3 signaling  
Toxicogenomic analyses of the effects of BDE-47/209, TBBPA/S and TCBPA on early neural development with a human embryonic stem cell in vitro differentiation system 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 379, 页码: -
Authors:  Liang, Shengxian;  Liang, Shaojun;  Yin, Nuoya;  Hu, Bowen;  Faiola, Francesco
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BDE-47/209  TBBPA/S  TCBPA  Human embryonic stem cells  Developmental neural toxicity  
Genetic diversity of diazotrophs and total bacteria in the phyllosphere of Pyrus serotina, Prunus armeniaca, Prunus avium, and Vitis vinifera 期刊论文
CANADIAN JOURNAL OF MICROBIOLOGY, 2019, 卷号: 65, 期号: 9, 页码: 642-652
Authors:  Liang, Shengxian;  Liu, Hao;  Wu, Shanghua;  Xu, Shengjun;  Jin, Decai;  Faiola, Francesco;  Zhuang, Xuliang;  Zhuang, Guoqiang;  Qu, Dong;  Fan, Haiyan;  Bai, Zhihui
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phyllosphere  diazotroph diversity  nifH  16S rDNA  clone library  
Embryonic stem cell- and transcriptomics-based in vitro analyses reveal that bisphenols A, F and S have similar and very complex potential developmental toxicities 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 176, 页码: 330-338
Authors:  Yin, Nuoya;  Liang, Xiaoxing;  Liang, Shengxian;  Lan, Shaojun;  Yang, Renjun;  Hu, Bowen;  Cheng, Zhanwen;  Liu, Shuyu;  Dong, Hengzhi;  Liu, Sijin;  Faiola, Francesco
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Mouse embryonic stem cells (mESCs)  Bisphenols A, F and S  Developmental toxicity  Stem cell toxicology  
Establishment of a human embryonic stem cell-based liver differentiation model for hepatotoxicity evaluations 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 174, 页码: 353-362
Authors:  Liang, Shengxian;  Liang, Shaojun;  Yin, Nuoya;  Faiola, Francesco
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Thyroid hormones (THs)  Polybrominated diphenyl ethers BDE-47/209  Human embryonic stem cells (ESCs)  Developmental hepatotoxicity  Endocrine-disrupting chemicals (EDCs)  
Human Pluripotent Stem Cells as Tools for Predicting Developmental Neural Toxicity of Chemicals: Strategies, Applications, and Challenges 期刊论文
STEM CELLS AND DEVELOPMENT, 2019, 卷号: 28, 期号: 12, 页码: 755-768
Authors:  Liang, Shengxian;  Yin, Nuoya;  Faiola, Francesco
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developmental neural toxicity (DNT)  human pluripotent stem cells (hPSCs)  neural differentiation  neurons  astrocytes  oligodendrocytes  
基于胚胎干细胞模型研究环境污染物对神经肝脏发育的干扰效应 学位论文
理学博士, 北京: 中国科学院生态环境研究中心, 2019
Authors:  梁胜贤
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环境污染物， 胚胎干细胞， 神经发育 毒性，肝 脏发育 毒性  Environmental Pollutants, Embryonic Stem Cells, Developmental Neural Toxicity, Developmental Hepatocytes Toxicity  
Monitoring Opportunistic Pathogens in Domestic Wastewater from a Pilot-Scale Anaerobic Biofilm Reactor to Reuse in Agricultural Irrigation 期刊论文
WATER, 2019, 卷号: 11, 期号: 6, 页码: -
Authors:  Cui, Bingjian;  Liang, Shengxian
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domestic wastewater  bacterial pathogens  qPCR  agricultural reuse  
5-fluorouracil-induced neurotoxicity in rat cerebellum granule cells involves oxidative stress and activation of caspase-3 pathway 期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2019, 卷号: 12, 期号: 3, 页码: 2334-2343
Authors:  Zhang, Yang;  Yin, Nuoya;  Liang, Shengxian;  Shen, Su;  Li, Dandan;  Faiola, Francesco
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5-fluorouracil  neurotoxicity  cerebellum granule cells  oxidative stress  caspase  
Evaluation of the early developmental neural toxicity of F-53B, as compared to PFOS, with an in vitro mouse stem cell differentiation model 期刊论文
CHEMOSPHERE, 2018, 卷号: 204, 页码: 109-118
Authors:  Yin, Nuoya;  Yang, Renjun;  Liang, Shaojun;  Liang, Shengxian;  Hu, Bowen;  Ruan, Ting;  Faiola, Francesco
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F-53B  Perfluorooctane sulfonate (PFOS)  Developmental neural toxicity  Embryonic stem cells (ESCs)  Neural differentiation  Neuroectoderm