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中国科学院生态环境研究中心
KMS of Research Center for Eco-Environmental Sciences, CAS
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中国科学院饮用水科学... [8]
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生态毒理学报 [3]
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酵母双杂交技术构建稀有鮈鲫不同雌激素受体亚型的重组荧光酵母
期刊论文
生态毒理学报, 2019, 卷号: 14, 期号: 5, 页码: 108-113
Authors:
季晓亚
;
杨明嘉
;
黄超
;
袁圣武
;
周小红
;
饶凯锋
;
马梅
;
王子健
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Submit date:2020/06/05
雌激素
17β-雌二醇
稀有鮈鲫
酵母双杂交
雌激素受体
荧光酵母
雌激素效应
Comparative toxicity study of a novel non-ionic surfactant, vanillin ethoxylates, and nonylphenol ethoxylates in Chinese hamster ovary cells in vitro
期刊论文
JOURNAL OF ENVIRONMENTAL SCIENCES, 2019, 卷号: 82, 页码: 70-81
Authors:
Yuan, Shengwu
;
Ji, Xiaoya
;
Ma, Mei
;
Ding, Fengmei
;
Rao, Kaifeng
;
Wang, Zijian
;
Yang, Rong
;
Liu, Yihong
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Submit date:2020/10/23
Vanillin ethoxylates (VAEOs)
Nonylphenol ethoxylates (NPEOs)
Cytotoxicity
Genotoxicity
Mitochondrial impairment
A comparison of endocrine disruption potential of nonylphenol ethoxylate, vanillin ethoxylate, 4-n-nonylphenol and vanillin in vitro
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 175, 页码: 208-214
Authors:
Ji, Xiaoya
;
Li, Na
;
Yuan, Shengwu
;
Zhou, Xiaohong
;
Ding, Fengmei
;
Rao, Kaifeng
;
Ma, Mei
;
Wang, Zijian
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Submit date:2020/10/23
Nonylphenol ethoxylate
Vanillin ethoxylate
4-n-nonylphenol
Vanillin
Nuclear receptors
Two-hybrid yeast
Aryl-phosphorus-containing flame retardants induce oxidative stress, the p53-dependent DNA damage response and mitochondrial impairment in A549 cells
期刊论文
ENVIRONMENTAL POLLUTION, 2019, 卷号: 250, 页码: 58-67
Authors:
Yuan, Shengwu
;
Han, Yingnan
;
Ma, Mei
;
Rao, Kaifeng
;
Wang, Zijian
;
Yang, Rong
;
Liu, Yihong
;
Zhou, Xiaohong
Adobe PDF(2643Kb)
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View/Download:2/0
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Submit date:2020/10/21
Phosphorus-containing flame retardants
Reactive oxygen species
Mitochondrial damage
p53 transfection
Gene expression
Toxicokinetic patterns, metabolites formation and distribution in various tissues of the Chinese rare minnow (Gobiocypris rarus) exposed to tri (2-butoxyethyl) phosphate (TBOEP) and tri-n-butyl phosphate (TNBP)
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2019, 卷号: 668, 页码: 806-814
Authors:
Hou, Rui
;
Yuan, Shengwu
;
Feng, Chenglian
;
Xu, Yiping
;
Rao, Kaifeng
;
Wang, Zijian
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Submit date:2020/10/23
Alkyl substituted organophosphate esters (alkyl-OPEs)
Toxicokinetic
Di-alkyl phosphate (DAP)
Hydroxylated organophosphate ester
Metabolite parent concentration factor
含磷阻燃剂和新型表面活性剂的离体毒性及毒性机制研究
学位论文
理学博士, 北京: 中国科学院生态环境研究中心, 2019
Authors:
袁圣武
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Submit date:2020/07/29
含磷阻燃剂 ,新型非离子表面活性剂 氧化损伤, Dna 损伤, 细胞周 期 阻滞
phosphorus Containing Flame Retardants, Novel Non Ionic Surfactant, Oxidative Stress, Dna Damage, Cell Cycle Arrest
Prediction of the combined effects of multiple estrogenic chemicals on MCF-7 human breast cancer cells and a preliminary molecular exploration of the estrogenic proliferative effects and related gene expression
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2018, 卷号: 160, 页码: 1-9
Authors:
Yuan, Shengwu
;
Huang, Chao
;
Ji, Xiaoya
;
Ma, Mei
;
Rao, Kaifeng
;
Wang, Zijian
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Submit date:2019/06/24
Environmental estrogens
Combined effects
Cell proliferation
Addition model
Estrogen receptors
Aryl- and alkyl-phosphorus-containing flame retardants induced mitochondrial impairment and cell death in Chinese hamster ovary (CHO-k1) cells
期刊论文
ENVIRONMENTAL POLLUTION, 2017, 卷号: 230, 期号: 0, 页码: 775-786
Authors:
Huang, Chao
;
Li, Na
;
Yuan, Shengwu
;
Ji, Xiaoya
;
Ma, Mei
;
Rao, Kaifeng
;
Wang, Zijian
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Submit date:2018/07/29
Hosphorus-containing Flame Retardants
High Content Screening
Mitochondrial Impairment
Cell Death
环境污染物导致氧化应激的关键信号通路及其检测方法
期刊论文
生态毒理学报, 2017, 期号: 01, 页码: 25-37
Authors:
袁圣武
;
黄超
;
季晓亚
;
马梅
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Submit date:2018/03/15
环境污染物
氧化应激
氧化损伤
信号通路
监测方法
环境雌激素生物效应的作用机制研究进展
期刊论文
生态毒理学报, 2017, 期号: 01, 页码: 38-51
Authors:
季晓亚
;
李娜
;
袁圣武
;
黄超
;
饶凯锋
;
马梅
;
王子健
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Submit date:2018/03/15
环境雌激素
核受体
膜受体
基因组
非基因组
信号通路