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Isotope Tracers To Study the Environmental Fate and Bioaccumulation of Metal-Containing Engineered Nanoparticles: Techniques and Applications
Yin, Yongguang; Tan, Zhiqiang; Hu, Ligang; Yu, Sujuan; Liu, Jingfu; Jiang, Guibin
2017-12-05
Source PublicationCHEMICAL REVIEWS
Volume117Issue:5Pages:4462-4487
AbstractThe rapidly growing applicability of metal-containing engineered nano particles (MENPs) has made their environmental fate, biouptake, and transformation important research topics. However, considering the relatively low concentration of MENPs and the high concentration of background metals in the environment and in organisms, tracking the fate of MENPs in environment-related scenarios remains a challenge. Intrinsic labeling of MENPs with radioactive or stable isotopes is a useful tool for the highly sensitive and selective detection of MENPs in the environment and organisms, thus enabling tracing of their transformation, uptake, distribution, and clearance. In this review, we focus on radioactive/stable isotope labeling of MENPs for their environmental and biological tracing. We summarize the advantages of intrinsic radioactive/stable isotopes for MENP labeling and discuss the considerations in labeling isotope selection and preparation of labeled MENPs, as well as exposure routes and detection of labeled MENPs. In addition, current practice in the use of radioactive/stable isotope labeling of MENPs to study their environmental fate and bioaccumulation is reviewed. Future perspectives and potential applications are also discussed, including imaging techniques for radioactive- and stable-isotope-labeled MENPs, hyphenated multistable isotope tracers with speciation analysis, and isotope fractionation as a MENP tracer. It is expected that this critical review could provide the necessary background information to further advance the applications of isotope tracers to study the environmental fate and bioaccumulation of MENPs.
Department环境化学与生态毒理学国家重点实验室
Document Type期刊论文
Identifierhttps://ir.rcees.ac.cn/handle/311016/39347
Collection环境化学与生态毒理学国家重点实验室
Recommended Citation
GB/T 7714
Yin, Yongguang,Tan, Zhiqiang,Hu, Ligang,et al. Isotope Tracers To Study the Environmental Fate and Bioaccumulation of Metal-Containing Engineered Nanoparticles: Techniques and Applications[J]. CHEMICAL REVIEWS,2017,117(5):4462-4487.
APA Yin, Yongguang,Tan, Zhiqiang,Hu, Ligang,Yu, Sujuan,Liu, Jingfu,&Jiang, Guibin.(2017).Isotope Tracers To Study the Environmental Fate and Bioaccumulation of Metal-Containing Engineered Nanoparticles: Techniques and Applications.CHEMICAL REVIEWS,117(5),4462-4487.
MLA Yin, Yongguang,et al."Isotope Tracers To Study the Environmental Fate and Bioaccumulation of Metal-Containing Engineered Nanoparticles: Techniques and Applications".CHEMICAL REVIEWS 117.5(2017):4462-4487.
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