RCEES OpenIR  > 城市与区域生态国家重点实验室
Toxicity and mechanisms of action of titanium dioxide nanoparticles in living organisms
Hou, Jing; Wang, Luyao; Wang, Chunjie; Zhang, Songlin; Liu, Haiqiang; Li, Shiguo; Wang, Xiangke
2019-01-01
Source PublicationJOURNAL OF ENVIRONMENTAL SCIENCES
ISSN1001-0742
Volume75Pages:40-53
AbstractTitanium dioxide nanoparticles (TiO2 NPs) are one of the most widely used nanomaterials in the consumer products, agriculture, and energy sectors. Their large demand and widespread applications will inevitably cause damage to organisms and ecosystems. A better understanding of TiO2 NP toxicity in living organisms may promote risk assessment and safe use practices of these nanomaterials. This reviewsummarizes the toxic effects of TiO2 NPs onmultiple taxa of microorganisms, algae, plants, invertebrates, and vertebrates. The mechanism of TiO2 NP toxicity to organisms can be outlined in three aspects: The Reactive Oxygen Species (ROS) produced by TiO2 NPs following the induction of electron-hole pairs; cellwall damage and lipid peroxidation of the cellmembrane caused byNP-cell attachment by electrostatic force owing to the large surface area of TiO2 NPs; and TiO2 NP attachment to intracellular organelles and biological macromolecules following damage to the cell membranes. (c) 2018 The Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences. Published by Elsevier B.V.
Department城市与区域生态国家重点实验室
KeywordTiO2 nanoparticles Particle size Exposure Oxidative stress Living organisms
Document Type期刊论文
Identifierhttps://ir.rcees.ac.cn/handle/311016/42874
Collection城市与区域生态国家重点实验室
Affiliation1.North China Elect Power Univ, Coll Environm Sci & Engn, Beijing 102206, Peoples R China
2.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, Beijing 100085, Peoples R China
Recommended Citation
GB/T 7714
Hou, Jing,Wang, Luyao,Wang, Chunjie,et al. Toxicity and mechanisms of action of titanium dioxide nanoparticles in living organisms[J]. JOURNAL OF ENVIRONMENTAL SCIENCES,2019,75:40-53.
APA Hou, Jing.,Wang, Luyao.,Wang, Chunjie.,Zhang, Songlin.,Liu, Haiqiang.,...&Wang, Xiangke.(2019).Toxicity and mechanisms of action of titanium dioxide nanoparticles in living organisms.JOURNAL OF ENVIRONMENTAL SCIENCES,75,40-53.
MLA Hou, Jing,et al."Toxicity and mechanisms of action of titanium dioxide nanoparticles in living organisms".JOURNAL OF ENVIRONMENTAL SCIENCES 75(2019):40-53.
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