| Toxicity and mechanisms of action of titanium dioxide nanoparticles in living organisms | |
| Hou, Jing; Wang, Luyao; Wang, Chunjie; Zhang, Songlin; Liu, Haiqiang; Li, Shiguo; Wang, Xiangke | |
| 2019-01-01 | |
| Source Publication | JOURNAL OF ENVIRONMENTAL SCIENCES
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| ISSN | 1001-0742 |
| Volume | 75Pages:40-53 |
| Abstract | Titanium dioxide nanoparticles (TiO2 NPs) are one of the most widely used nanomaterials in the consumer products, agriculture, and energy sectors. Their large demand and widespread applications will inevitably cause damage to organisms and ecosystems. A better understanding of TiO2 NP toxicity in living organisms may promote risk assessment and safe use practices of these nanomaterials. This reviewsummarizes the toxic effects of TiO2 NPs onmultiple taxa of microorganisms, algae, plants, invertebrates, and vertebrates. The mechanism of TiO2 NP toxicity to organisms can be outlined in three aspects: The Reactive Oxygen Species (ROS) produced by TiO2 NPs following the induction of electron-hole pairs; cellwall damage and lipid peroxidation of the cellmembrane caused byNP-cell attachment by electrostatic force owing to the large surface area of TiO2 NPs; and TiO2 NP attachment to intracellular organelles and biological macromolecules following damage to the cell membranes. (c) 2018 The Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences. Published by Elsevier B.V. |
| Department | 城市与区域生态国家重点实验室 |
| Keyword | TiO2 nanoparticles Particle size Exposure Oxidative stress Living organisms |
| Document Type | 期刊论文 |
| Identifier | https://ir.rcees.ac.cn/handle/311016/42874 |
| Collection | 城市与区域生态国家重点实验室 |
| Affiliation | 1.North China Elect Power Univ, Coll Environm Sci & Engn, Beijing 102206, Peoples R China 2.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, Beijing 100085, Peoples R China |
| Recommended Citation GB/T 7714 | Hou, Jing,Wang, Luyao,Wang, Chunjie,et al. Toxicity and mechanisms of action of titanium dioxide nanoparticles in living organisms[J]. JOURNAL OF ENVIRONMENTAL SCIENCES,2019,75:40-53. |
| APA | Hou, Jing.,Wang, Luyao.,Wang, Chunjie.,Zhang, Songlin.,Liu, Haiqiang.,...&Wang, Xiangke.(2019).Toxicity and mechanisms of action of titanium dioxide nanoparticles in living organisms.JOURNAL OF ENVIRONMENTAL SCIENCES,75,40-53. |
| MLA | Hou, Jing,et al."Toxicity and mechanisms of action of titanium dioxide nanoparticles in living organisms".JOURNAL OF ENVIRONMENTAL SCIENCES 75(2019):40-53. |
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| Toxicity and mechani（1959KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Download | |
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