|Effect of dietary vitamins in oral bioaccessibility of lead in contaminated soils based on the physiologically based extraction test|
|Yin, Naiyi; Han, Zeliang; Du, Huili; Wang, Pengfei; Li, Yunpeng; Chen, Xiaochen; Sun, Guoxin; Cui, Yanshan; Hu, Zhengyi
|Source Publication||SCIENCE OF THE TOTAL ENVIRONMENT
|Abstract||To determine the effect of vitamin supplements on the oral bioaccessibility of Pb in soils, Pb bioaccessibility was measured in the presence of 9 vitamins by a physiologically based extraction test. Gastric Pb bioaccessibility (G-BA, 2.6-83.3%) was found to be mostly reduced (1.1-3.1 fold) in the presence of B vitamins, specifically vitamins B1, B6, and B9. In contrast, a significant increase in Pb G-BA was observed with vitamin C and E involved. In the small intestinal phases, Pb bioaccessibility (I-BA) ranged from 0.1% to 16.0%, being 5-50 fold lower than the corresponding G-BA values. Vitamin C supplementation showed a 7-fold increase in Pb I-BA, with a similar increase presented in approximately 30% of samples treated to vitamin B involvement. Lead liberation in gastrointestinal digests was associated with the dissolution of Fe and Mn regulated by vitamins. In conclusion, the addition of B vitamins resulted in the reduction of gastric Pb bioaccessibility, but the bioaccessibility value increased in participation of vitamin C and E. Elevated intestinal bioaccessibility was found especially for vitamin C. This should contribute to more accurate assessment of health risks from contaminated soils. Nutritional management aimed at preventing Pb-induced toxicity can benefit from knowledge of vitamin influence on soil Pb bioaccessibility. (C) 2020 Elsevier B.V. All rights reserved.|
Yin, Naiyi,Han, Zeliang,Du, Huili,et al. Effect of dietary vitamins in oral bioaccessibility of lead in contaminated soils based on the physiologically based extraction test[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2020,747:1-10.
Yin, Naiyi.,Han, Zeliang.,Du, Huili.,Wang, Pengfei.,Li, Yunpeng.,...&Hu, Zhengyi.(2020).Effect of dietary vitamins in oral bioaccessibility of lead in contaminated soils based on the physiologically based extraction test.SCIENCE OF THE TOTAL ENVIRONMENT,747,1-10.
Yin, Naiyi,et al."Effect of dietary vitamins in oral bioaccessibility of lead in contaminated soils based on the physiologically based extraction test".SCIENCE OF THE TOTAL ENVIRONMENT 747(2020):1-10.
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