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Alternaria Mycotoxins: An Overview of Toxicity, Metabolism, and Analysis in Food
Chen, Anqi; Mao, Xin; Sun, Qinghui; Wei, Zixuan; Li, Juan; You, Yanli; Zhao, Jiqiang; Jiang, Guibin; Wu, Yongning; Wang, Liping; Li, Yanshen
2021-07-21
Source PublicationJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
ISSN0021-8561
Volume69Issue:28Pages:7817-7830
AbstractThe genus Alternaria is widely distributed in the environment. Numerous species of the genus Alternaria can produce a variety of toxic secondary metabolites, called Alternaria mycotoxins. In this review, natural occurrence, toxicity, metabolism, and analytical methods are introduced. The contamination of these toxins in foodstuffs is ubiquitous, and most of these metabolites present genotoxic and cytotoxic effects. Moreover, Alternaria toxins are mainly hydroxylated to catechol metabolites and combined with sulfate and glucuronic acid in in vitro arrays. A more detailed summary of the metabolism of Alternaria toxins is presented in this work. To effectively detect and determine the mycotoxins in food, analytical methods with high sensitivity and good accuracy are also reviewed. This review will guide the formulation of maximum residue limit standards in the future, covering both toxicity and metabolic mechanism of Alternaria toxins.
Department环境化学与生态毒理学国家重点实验室
KeywordAlternaria mycotoxins food toxicity metabolic mechanism analytical method
WOS Research AreaAgriculture, Multidisciplinary ; Chemistry, Applied ; Food Science & Technology
Document Type期刊论文
Identifierhttps://ir.rcees.ac.cn/handle/311016/45655
Collection环境化学与生态毒理学国家重点实验室
Affiliation1.Yantai Univ, Coll Life Sci, Yantai 264005, Shandong, Peoples R China
2.Univ Western Ontario, Dept Chem & Biochem Engn, London, ON N6A 5B9, Canada
3.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China
4.Chinese Acad Med Sci, China Natl Ctr Food Safety Risk Assessment, NHC Key Lab Food Safety Risk Assessment, Res Unit 20
5.Huazhong Agr Univ, Coll Plant Sci & Technol, Wuhan 430070, Hubei, Peoples R China
Recommended Citation
GB/T 7714
Chen, Anqi,Mao, Xin,Sun, Qinghui,et al. Alternaria Mycotoxins: An Overview of Toxicity, Metabolism, and Analysis in Food[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2021,69(28):7817-7830.
APA Chen, Anqi.,Mao, Xin.,Sun, Qinghui.,Wei, Zixuan.,Li, Juan.,...&Li, Yanshen.(2021).Alternaria Mycotoxins: An Overview of Toxicity, Metabolism, and Analysis in Food.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,69(28),7817-7830.
MLA Chen, Anqi,et al."Alternaria Mycotoxins: An Overview of Toxicity, Metabolism, and Analysis in Food".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 69.28(2021):7817-7830.
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