| A pilot evaluation on the toxicokinetics and bioaccumulation of polychlorinated naphthalenes in laying hens | |
Wang, Chu; Dong, Shujun; Wang, Pu; Hao, Yanfen; Wang, Ruiguo; Zhang, Su; Wang, Yaxin; Wang, Peilong; Zhang, Qinghua; Jiang, Guibin
| |
| 2022-08-20 | |
| Source Publication | SCIENCE OF THE TOTAL ENVIRONMENT
 |
| ISSN | 0048-9697 |
| Volume | 835Issue:0Pages:155454 |
| Abstract | Knowledge of the transfer features of polychlorinated naphthalenes (PCNs), a class of emerging persistent organic pollutants (POPs), is still lacking concerning the environment-feed-food transfer chain of farm animals. We conducted a controlled feeding experiment with laying hens fed fly ash-contaminated diets to investigate the toxicokinetics and bioaccumulation of PCNs (tri-to octa-CNs) in the hen eggs and tissues. The eggs showed increasing PCNs levels after 14 days of oral exposure, which gradually decreased during the 28-day depuration period but still exceeded the initial levels. The apparent one-compartment half-life of sigma(63)PCNs in the eggs was 28.9 days, which was comparable to those of other dioxin-like compounds. The uptake and depuration rates of PCN congeners in the eggs were 0.002-0.010 and 0.016-0.079 days(-1) in eggs, respectively. The depuration rates were decreased with the n-octanol/water partition coefficients (logK(OW)), indicating that the eggs retained more lipophilic congeners, whereas the uptake rates increased with the logK(OW), indicating the faster deposition of the more lipophilic PCNs in eggs during the exposure period. The transfer rates of PCN congeners ranged from 0.27%-23.0%, indicating the transfer potential of PCNs from feed to eggs. Additionally, the PCN distribution in the laying hens at the end of the exposure showed tissue-specific accumulation, with the high levels of PCNs in the liver, spleen, and ovum. Positive correlations between the transfer factors (C-tissue/C-feed) and the logK(OW) suggested that more lipophilic PCN congeners tended to accumulate in the tissues. After quantitatively assessing the feed-to-food transfer of PCNs in laying hens, our results highlight the risk of exposure to PCNs in the food supply chain. |
| Department | 环境化学与生态毒理学国家重点实验室 ; 环境化学与生态毒理学国家重点实验室 |
| Keyword | BIPHENYLS PCBS P-DIOXINS PCNS FOOD EGGS CONTAMINATION PCDD/FS TRENDS FEED BIOMAGNIFICATION |
| Document Type | 期刊论文 |
| Identifier | https://ir.rcees.ac.cn/handle/311016/47455 |
| Collection | 环境化学与生态毒理学国家重点实验室 |
| Corresponding Author | Dong, Shujun |
| Affiliation | 1.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China 2.Chinese Acad Agr Sci, Inst Qual Stand & Testing Technol Agroprod, Beijing 100081, Peoples R China 3.Jianghan Univ, Sch Environm & Hlth, Hubei Key Lab Ind Fume & Dust Pollut Control, Wuhan 430056, Peoples R China 4.Univ Chinese Acad Sci, Sino Danish Coll, Beijing 100049, Peoples R China 5.Univ Chinese Acad Sci, Sch Environm, Hangzhou Inst Adv Study, Hangzhou 310000, Peoples R China |
| Recommended Citation GB/T 7714 | Wang, Chu,Dong, Shujun,Wang, Pu,et al. A pilot evaluation on the toxicokinetics and bioaccumulation of polychlorinated naphthalenes in laying hens[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2022,835(0):155454. |
| APA | Wang, Chu.,Dong, Shujun.,Wang, Pu.,Hao, Yanfen.,Wang, Ruiguo.,...&Jiang, Guibin.(2022).A pilot evaluation on the toxicokinetics and bioaccumulation of polychlorinated naphthalenes in laying hens.SCIENCE OF THE TOTAL ENVIRONMENT,835(0),155454. |
| MLA | Wang, Chu,et al."A pilot evaluation on the toxicokinetics and bioaccumulation of polychlorinated naphthalenes in laying hens".SCIENCE OF THE TOTAL ENVIRONMENT 835.0(2022):155454. |
| Files in This Item: | Download All | |||||
| File Name/Size | DocType | Version | Access | License | ||
| A pilot evaluation o（1950KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Download | |
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment