| Evaluating the inhalation bioaccessibility of traffic-impacted particulate matter-bound PAHs in a road tunnel by simulated lung fluids | |
Shi, Fengqiong; Ju, Jingxue; Zhang, Xian; Zheng, Ronggang ; Xiong, Feng; Liu, Jingfu
| |
| 2022-08-01 | |
| Source Publication | SCIENCE OF THE TOTAL ENVIRONMENT
 |
| ISSN | 0048-9697 |
| Volume | 832Issue:0Pages:155046 |
| Abstract | Polycyclic aromatic hydrocarbons (PAHs) are the most highly concerned pollutants bound on traffic-impacted particulate matter (TIPM). The inhaled TIPM-bound PAHs risk has attracted much attention, whereas the inhalation bioaccessibility, a method to refine the exposure risk assessment, has not yet been extensively introduced in the exposure risk assessment. Thus, in vitro assays using artificial lung fluids including artificial lysosomal fluid (ALF), Gamble's solution (GS), and modified GS (MGS) were conducted to assess the inhalation bioaccessibility of USEPA 16 PAHs in TIPM collected from an expressway tunnel, the influence factors of PAHs' inhalation bioaccessibility were explored, and the exposure risk of TIPM-bound PAHs was estimated based on inhalation bioaccessibility. Results showed that the average PAHs concentrations were 30.5 +/- 12.9 ng/m(3), 36.2 +/- 5.19 ng/m(3), and 39.9 +/- 4.31 ng/m(3) in the tunnel inlet PM2.5, TSP, and tunnel center PM2.5, respectively. Phe, Flt, Pyr, Nap, Chr, BbF, and BkF were found as the dominant species in TSP and PM2.5, indicating a dominant contribution of PAHs from diesel-fueled vehicular emissions. The bioaccessible fractions measured for different PAH species in tunnel PM2.5 and TSP were highly variable, which can be attributed to PAHs' physicochemical properties, size, and carbonaceous materials of TIPM. The addition of Tenax into SLF as an adsorption sink can greatly increase PAHs' inhalation bioaccessibility, but DPPC has a limited effect on tunnel PM-bound PAHs' bioaccessibility. The incremental lifetime carcinogenic risk (ILCR) of tunnel inlet PM2.5-bound PAHs evaluated according to their total mass concentration exceeded the threshold (1.0 x 10(-6)) set by the USEPA, whereas the ILCRs estimated based on the inhalation bioaccessibility were far below the threshold. Hence, it is vitally important to take into consideration of pollutant's bioaccessibility to refine health risk assessment. |
| Department | 环境化学与生态毒理学国家重点实验室 ; 环境化学与生态毒理学国家重点实验室 |
| Keyword | POLYCYCLIC AROMATIC-HYDROCARBONS ELEMENTAL CARBON FLAME RETARDANTS TENAX SIZE EMISSION VEHICLES PARTICLES EXPOSURE DUST |
| Document Type | 期刊论文 |
| Identifier | https://ir.rcees.ac.cn/handle/311016/47530 |
| Collection | 环境化学与生态毒理学国家重点实验室 |
| Corresponding Author | Liu, Jingfu |
| Affiliation | 1.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China 2.Chinese Acad Sci, Innovat Acad Green Manufacture, Inst Proc Engn, Beijing 100190, Peoples R China 3.Hebei Univ, Coll Publ Hlth, Baoding 071002, Peoples R China 4.JiangXi Gannan Highway Survey & Design Inst, Ganzhou 341000, Peoples R China |
| Recommended Citation GB/T 7714 | Shi, Fengqiong,Ju, Jingxue,Zhang, Xian,et al. Evaluating the inhalation bioaccessibility of traffic-impacted particulate matter-bound PAHs in a road tunnel by simulated lung fluids[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2022,832(0):155046. |
| APA | Shi, Fengqiong,Ju, Jingxue,Zhang, Xian,Zheng, Ronggang,Xiong, Feng,&Liu, Jingfu.(2022).Evaluating the inhalation bioaccessibility of traffic-impacted particulate matter-bound PAHs in a road tunnel by simulated lung fluids.SCIENCE OF THE TOTAL ENVIRONMENT,832(0),155046. |
| MLA | Shi, Fengqiong,et al."Evaluating the inhalation bioaccessibility of traffic-impacted particulate matter-bound PAHs in a road tunnel by simulated lung fluids".SCIENCE OF THE TOTAL ENVIRONMENT 832.0(2022):155046. |
| Files in This Item: | Download All | |||||
| File Name/Size | DocType | Version | Access | License | ||
| Evaluating the inhal（1536KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Download | |
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment