| Estrogen-like response of perfluorooctyl iodide in male medaka (Oryzias latipes) based on hepatic vitellogenin induction | |
| Wang, Yichen; Zhou, Qunfang; Wang, Chang; Yin, Nuoya; Li, Zhuona; Liu, Jiyan; Jiang, Guibin; Jiang, GB | |
| 2013 | |
| Source Publication | ENVIRONMENTAL TOXICOLOGY
 |
| Volume | 28Issue:10Pages:571-578 |
| Abstract | Using the in vivo male medaka model, we investigated the estrogen-like response of perfluorooctyl iodide (PFOI) which is a potential source of perfluorinated carboxylic acids. Using real-time quantitative polymerase chain reaction, the expression levels of related estrogenic genes including estrogenic receptor (ER), ER, vitellogenin I (VTG I), and VTG II in the livers of male medaka exposed to PFOI were analyzed. The results showed that PFOI upregulated the expression levels of the tested genes in a dose-dependent manner. VTG protein levels increased in both dose- and time-dependent manners due to PFOI exposure. The results suggested that PFOI is a potential estrogenic compound. (c) 2011 Wiley Periodicals, Inc. Environ Toxicol 28: 571-578, 2013. |
| Department | 环境化学与生态毒理学国家重点实验室 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | https://ir.rcees.ac.cn/handle/311016/7470 |
| Collection | 环境化学与生态毒理学国家重点实验室 |
| Corresponding Author | Jiang, GB |
| Recommended Citation GB/T 7714 | Wang, Yichen,Zhou, Qunfang,Wang, Chang,et al. Estrogen-like response of perfluorooctyl iodide in male medaka (Oryzias latipes) based on hepatic vitellogenin induction[J]. ENVIRONMENTAL TOXICOLOGY,2013,28(10):571-578. |
| APA | Wang, Yichen.,Zhou, Qunfang.,Wang, Chang.,Yin, Nuoya.,Li, Zhuona.,...&Jiang, GB.(2013).Estrogen-like response of perfluorooctyl iodide in male medaka (Oryzias latipes) based on hepatic vitellogenin induction.ENVIRONMENTAL TOXICOLOGY,28(10),571-578. |
| MLA | Wang, Yichen,et al."Estrogen-like response of perfluorooctyl iodide in male medaka (Oryzias latipes) based on hepatic vitellogenin induction".ENVIRONMENTAL TOXICOLOGY 28.10(2013):571-578. |
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