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Structure-Activity Relationship Investigation on Reaction Mechanism between Chlorinated Quinoid Carcinogens and Clinically-Used Aldoxime Nerve-Agent Antidote under Physiological Condition 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2021, 卷号: 34, 期号: 4, 页码: 1091-1100
Authors:  Xie, Lin-Na;  Huang, Chun-Hua;  Xu, Dan;  Qin, Li;  Li, Feng;  Shan, Guo-Qiang;  Liu, Zhi-Sheng;  Cao, Dong;  Geng, Fang-Lan;  Mao, Li;  Shao, Jie;  Sheng, Zhi-Guo;  Zhu, Ben-Zhan
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The critical role of unique azido-substituted chloro-O-semiquinone radical intermediates in the synergistic toxicity between sodium azide and chlorocatecholic carcinogens 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2021, 卷号: 10, 期号: 11, 页码: -
Authors:  Huang, Chun-Hua;  Tang, Miao;  Xu, Dan;  Shao, Bo;  Li, Pei-Lin;  Tang, Tian-Shu;  Qin, Li;  Zhu, Ben-Zhan
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urban metabolism  structural equation model  household food consumption  food-sourced nitrogen  environmental emissions  
Unusual Two-Step Claisen-type Rearrangement Reaction under Physiological Conditions 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 85, 期号: 23, 页码: 14945-14953
Authors:  Huang, Chun-Hua;  Xu, Dan;  Qin, Li;  Li, Pei-Lin;  Tang, Tian-Shu;  Zhu, Ben-Zhan
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Potent Oxidation of DNA by Haloquinoid Disinfection Byproducts to the More Mutagenic Imidazolone dlz via an Unprecedented Haloquinone-Enoxy Radical-Mediated Mechanism 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2020, 卷号: 54, 期号: 10, 页码: 6244-6253
Authors:  Shao, Jie;  Huang, Chun-Hua;  Shao, Bo;  Qin, Li;  Xu, Dan;  Li, Feng;  Qu, Na;  Xie, Lin-Na;  Kalyanaraman, Balaraman;  Zhu, Ben-Zhan
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Endosulfan promotes cell migration via PTP4A3-mediated signaling pathways in HUVECs 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 192, 页码: 1-9
Authors:  Li, Heng;  Liu, Shiqi;  Hu, Yumeng;  Zhao, Bin;  Sun, Yeqing;  Xu, Dan
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Endosulfan  Cell migration  PTP4A3  Signaling pathway  Endothelial cells  
An unexpected antioxidant and redox activity for the classic copper-chelating drug penicillamine 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2020, 卷号: 147, 页码: 150-158
Authors:  Mao, Li;  Huang, Chun-Hua;  Shao, Jie;  Qin, Li;  Xu, Dan;  Shao, Bo;  Zhu, Ben-Zhan
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Penicillamine  Antioxidant-like activity  Tetrachlorohydroquinone  Tetrachlorosemiquinone radical  Redox reaction  Autooxidation  
An unexpected new pathway for nitroxide radical production via more reactve nitrogen-centered amidyl radical intermediate during detoxification of the carcinogenic halogenated quinones by N-alkyl hydroxamic acids 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2020, 卷号: 146, 页码: 150-159
Authors:  Zhu, Ben-Zhan;  Xu, Dan;  Qin, Li;  Huang, Chun-Hua;  Xie, Lin-Na;  Mao, Li;  Shao, Jie;  Kalyanaraman, Balaraman
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N-centered amidyl radical  Nitroxide radical  Hydrogen-abstraction  Tetrachloroquinoid compounds  N-alkyl hydroxamic acids  
Unexpected activation of N-alkyl hydroxamic acids to produce reactive N-centered free radicals and DNA damage by carcinogenic chlorinated quinones under normal physiological conditions 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2020, 卷号: 146, 页码: 70-78
Authors:  Huang, Chun-Hua;  Xu, Dan;  Qin, Li;  Tang, Tian-Shu;  Shan, Guo-Qiang;  Xie, Lin-Na;  Li, Pei-Lin;  Mao, Li;  Shao, Jie;  Zhu, Ben-Zhan
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N-alkyl hydroxamic acids  N-centered radicals  Chlorinated quinones  Carbon-nitrogen bonding conjugate  DNA adducts  
Molecular mechanism for the activation of the anti-tuberculosis drug isoniazid by Mn(III): First detection and unequivocal identification of the critical N-centered isoniazidyl radical and its exact location 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2019, 卷号: 143, 页码: 232-239
Authors:  Qin, Li;  Huang, Chun-Hua;  Xu, Dan;  Xie, Lin-Na;  Shao, Jie;  Mao, Li;  Kalyanaraman, Balaraman;  Zhu, Ben-Zhan
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Isoniazid  Mn(III)(Acetate) 3  Isoniazidyl radical  Distal-nitrogen of the hydrazine group  Diisonicotinyl hydrazine  
Mechanism of unprecedented hydroxyl radical production and site-specific oxidative DNA damage by photoactivation of the classic arylhydroxamic acid carcinogens 期刊论文
CARCINOGENESIS, 2019, 卷号: 40, 期号: 9, 页码: 1153-1163
Authors:  Xu, Dan;  Huang, Chun-Hua;  Xie, Lin-Na;  Shao, Bo;  Mao, Li;  Shao, Jie;  Kalyanaraman, Balaraman;  Zhu, Ben-Zhan
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