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Nongenomic effects and mechanistic study of butyl benzyl phthalate-induced thyroid disruption: Based on integrated in vitro, in silico assays and proteome analysis 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 卷号: 836, 期号: 0, 页码: 155715
Authors:  Li, Jian;  Xu, Ying;  Jiang, Yuhao;  Li, Na;  Li, Zhanjie;  Kong, Dongdong;  Guo, Xueru;  Zhang, Junbo;  Zuo, Rui
View  |  Adobe PDF(1763Kb)  |  Favorite  |  View/Download:1/0  |  Submit date:2022/11/09
HORMONE  CELLS  RECEPTOR  ALPHA(V)BETA(3)  PROLIFERATION  ACTIVATION  TOXICITY  EXPOSURE  GROWTH  ESTERS  
Thyroid Hormone Disruption by Organophosphate Esters Is Mediated by Nuclear/Membrane Thyroid Hormone Receptors: In Vitro, In Vivo, and In Silico Studies 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2022, 卷号: 56, 期号: 7, 页码: 4241-4250
Authors:  Li, Jian;  Xu, Ying;  Li, Na;  Zuo, Rui;  Zhai, Yuanzheng;  Chen, Haiyang
View  |  Adobe PDF(2810Kb)  |  Favorite  |  View/Download:13/1  |  Submit date:2022/11/09
FLAME RETARDANTS  INTEGRIN ALPHA(V)BETA(3)  TRIPHENYL PHOSPHATE  EXPOSURE  ALPHA-V-BETA-3  EMBRYOS/LARVAE  ACTIVATION  TOXICITY  ANIMALS  TDCPP  
Multiple bioanalytical methods reveal a thyroid-disrupting mechanism related to the membrane receptor integrin alpha(v)beta(3) 期刊论文
ENVIRONMENTAL POLLUTION, 2021, 卷号: 279, 页码: -
Authors:  Kong, Dongdong;  Li, Jian;  Li, Na;  Zhang, Shurong;  Xu, Ying
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DEHP  Thyroid-disrupting effect  Toxic mechanism  Integrin alpha(v)beta(3)  ERK1/2  
TDCPP mimics thyroid hormones associated with the activation of integrin alpha(v)beta(3) and ERK1/2 期刊论文
CHEMOSPHERE, 2020, 卷号: 256, 页码: 1-9
Authors:  Li, Jian;  Liu, Hedan;  Li, Na;  Wang, Jinsheng;  Song, Liuting
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TDCPP  BDCPP  Thyroid disruption  Integrin alpha(v)beta(3)  ERK1/2  
Competitive binding assays for measuring the binding affinity of thyroid-disrupting chemicals for integrin alpha(v)beta(3) 期刊论文
CHEMOSPHERE, 2020, 卷号: 249, 页码: 1-8
Authors:  Li, Jian;  Liu, Hedan;  Zuo, Rui;  Yang, Jie;  Li, Na
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Thyroid-disrupting chemicals  Integrin alpha(v)beta(3)  Competitive binding assay  T4-BSA-F  Tc-99m-3PRGD(2)  Phthalate esters  
Mechanism of the Endocrine-Disruptive Effects of Low-Dose Bisphenol A via Transmembrane Receptor 期刊论文
PROGRESS IN CHEMISTRY, 2019, 卷号: 31, 期号: 1, 页码: 167-179
Authors:  Zhu, Benzhan;  Shen, Chen;  Sheng, Zhiguo
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bisphenol A  low-dose effect  G protein-coupled receptor 30  integrin alpha v beta 3  toxic effect  
Molecular mechanism of endocrine-disruptive effects induced by Bisphenol A: The role of transmembrane G-protein estrogen receptor 1 and integrin alpha v beta 3 期刊论文
JOURNAL OF ENVIRONMENTAL SCIENCES, 2019, 卷号: 75, 页码: 1-13
Authors:  Sheng, Zhiguo;  Wang, Cong;  Ren, Furong;  Liu, Yuxiang;  Zhu, Benzhan
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Bisphenol A  Low-dose effects  G protein-coupled estrogen receptor 1  Integrin alpha v beta 3  Reproductive toxicity  Thyroxine interference effect