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中国科学院生态环境研究中心
KMS of Research Center for Eco-Environmental Sciences, CAS
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Serum concentrations of per-/polyfluoroalkyl substances and its association with renal function parameters among teenagers near a Chinese fluorochemical industrial plant: A cross-sectional study
期刊论文
ENVIRONMENTAL POLLUTION, 2022, 卷号: 302, 期号: 0, 页码: 119020
Authors:
Xie, Lin-Na
;
Wang, Xiao-Chen
;
Su, Li-Qin
;
Ji, Sai-Sai
;
Dong, Xiao-Jie
;
Zhu, Hui-Juan
;
Hou, Sha-Sha
;
Wang, Cong
;
Li, Zhen-Huan
;
Dong, Bing
;
Zhu, Ying
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View/Download:5/0
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Submit date:2022/11/07
CHRONIC KIDNEY-DISEASE
PERFLUOROOCTANOIC ACID PFOA
C8 HEALTH PROJECT
BODY-MASS INDEX
PERFLUOROALKYL ACIDS
HUMAN EXPOSURE
CREATININE RATIO
BIRTH-WEIGHT
PARK
BIOACCUMULATION
Structure-Activity Relationship Investigation on Reaction Mechanism between Chlorinated Quinoid Carcinogens and Clinically-Used Aldoxime Nerve-Agent Antidote under Physiological Condition
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2021, 卷号: 34, 期号: 4, 页码: 1091-1100
Authors:
Xie, Lin-Na
;
Huang, Chun-Hua
;
Xu, Dan
;
Qin, Li
;
Li, Feng
;
Shan, Guo-Qiang
;
Liu, Zhi-Sheng
;
Cao, Dong
;
Geng, Fang-Lan
;
Mao, Li
;
Shao, Jie
;
Sheng, Zhi-Guo
;
Zhu, Ben-Zhan
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Submit date:2021/12/22
Concentration, spatial distribution, and health risk assessment of PFASs in serum of teenagers, tap water and soil near a Chinese fluorochemical industrial plant
期刊论文
ENVIRONMENT INTERNATIONAL, 2021, 卷号: 146, 页码: -
Authors:
Xie, Lin-Na
;
Wang, Xiao-Chen
;
Dong, Xiao-Jie
;
Su, Li-Qin
;
Zhu, Hui-Juan
;
Wang, Cong
;
Zhang, Dian-Ping
;
Liu, Fang-Ying
;
Hou, Sha-Sha
;
Dong, Bing
;
Shan, Guo-Qiang
;
Zhang, Xu
;
Zhu, Ying
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View/Download:51/15
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Submit date:2021/12/21
PFOA
Soil
Serum
Tap water
Health risk assessment
Potent Oxidation of DNA by Haloquinoid Disinfection Byproducts to the More Mutagenic Imidazolone dlz via an Unprecedented Haloquinone-Enoxy Radical-Mediated Mechanism
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2020, 卷号: 54, 期号: 10, 页码: 6244-6253
Authors:
Shao, Jie
;
Huang, Chun-Hua
;
Shao, Bo
;
Qin, Li
;
Xu, Dan
;
Li, Feng
;
Qu, Na
;
Xie, Lin-Na
;
Kalyanaraman, Balaraman
;
Zhu, Ben-Zhan
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Submit date:2021/09/14
An unexpected new pathway for nitroxide radical production via more reactve nitrogen-centered amidyl radical intermediate during detoxification of the carcinogenic halogenated quinones by N-alkyl hydroxamic acids
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2020, 卷号: 146, 页码: 150-159
Authors:
Zhu, Ben-Zhan
;
Xu, Dan
;
Qin, Li
;
Huang, Chun-Hua
;
Xie, Lin-Na
;
Mao, Li
;
Shao, Jie
;
Kalyanaraman, Balaraman
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Submit date:2021/09/14
N-centered amidyl radical
Nitroxide radical
Hydrogen-abstraction
Tetrachloroquinoid compounds
N-alkyl hydroxamic acids
Unexpected activation of N-alkyl hydroxamic acids to produce reactive N-centered free radicals and DNA damage by carcinogenic chlorinated quinones under normal physiological conditions
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2020, 卷号: 146, 页码: 70-78
Authors:
Huang, Chun-Hua
;
Xu, Dan
;
Qin, Li
;
Tang, Tian-Shu
;
Shan, Guo-Qiang
;
Xie, Lin-Na
;
Li, Pei-Lin
;
Mao, Li
;
Shao, Jie
;
Zhu, Ben-Zhan
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Submit date:2021/09/14
N-alkyl hydroxamic acids
N-centered radicals
Chlorinated quinones
Carbon-nitrogen bonding conjugate
DNA adducts
Molecular mechanism for the activation of the anti-tuberculosis drug isoniazid by Mn(III): First detection and unequivocal identification of the critical N-centered isoniazidyl radical and its exact location
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2019, 卷号: 143, 页码: 232-239
Authors:
Qin, Li
;
Huang, Chun-Hua
;
Xu, Dan
;
Xie, Lin-Na
;
Shao, Jie
;
Mao, Li
;
Kalyanaraman, Balaraman
;
Zhu, Ben-Zhan
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Submit date:2020/09/10
Isoniazid
Mn(III)(Acetate) 3
Isoniazidyl radical
Distal-nitrogen of the hydrazine group
Diisonicotinyl hydrazine
Mechanism of unprecedented hydroxyl radical production and site-specific oxidative DNA damage by photoactivation of the classic arylhydroxamic acid carcinogens
期刊论文
CARCINOGENESIS, 2019, 卷号: 40, 期号: 9, 页码: 1153-1163
Authors:
Xu, Dan
;
Huang, Chun-Hua
;
Xie, Lin-Na
;
Shao, Bo
;
Mao, Li
;
Shao, Jie
;
Kalyanaraman, Balaraman
;
Zhu, Ben-Zhan
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  |  
Submit date:2020/09/10
An unusual double radical homolysis mechanism for the unexpected activation of the aldoxime nerve-agent antidotes by polyhalogenated quinoid carcinogens under normal physiological conditions
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2019, 卷号: 130, 页码: 1-7
Authors:
Xie, Lin-Na
;
Shao, Jie
;
Huang, Chun-Hua
;
Li, Feng
;
Xu, Dan
;
Kalyanaraman, Balaraman
;
Zhu, Ben-Zhan
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Submit date:2020/10/21
Radical homolysis mechanism
Iminyl radical
Tetrachloro-1, 4-benzoquinone (TCBQ)
Pyridinium aldoximes
Nerve-agent antidotes
Polyhalogenated quinoid carcinogens
醛肟类神经性毒剂防治药物的新型解毒分子作用机制
期刊论文
中国科学:化学, 2018, 卷号: 48, 期号: 10, 页码: 1247-1259
Authors:
任福荣
;
肖璇
;
谢琳娜
;
徐丹
;
邵杰
;
黄春华
;
朱本占
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Submit date:2019/03/14
Beckmann裂解反应
吡啶盐醛肟
神经性毒剂防治药物
四氯-1,4-苯醌
解毒机理